The Magpies and the Kangaroos face off at the MCG on Saturday at 7.40pm.
Five players are absent from Collingwood’s squad.
One player is still recovering after a vehicle accident left him unconscious in training.
North Melbourne’s reserve team defeated North’s youngsters in the previous game by 43 points.
That win has supplied the seniors extra confidence.
The two sides want a strong beginning to the latter half of the season.